Preconception care: it’s never too early

Preconception care: it’s never too early

The preconception window has been recognized as one of the earliest sensitive windows of human development, and interventions that focus on this period have the potential to affect not only pregnancy but long term outcomes as well. The journal Reproductive Health has published a supplement entitled 'Preconception Interventions' which includes a series of systematic reviews regarding the impact ...

Dementia risk reduction: it's never too early, it's never too late.

Never Too Early, Never Too Late: Effects of Search Timing on Product Innovation

A significant stream of research has emerged to study search (i.e., problem-solving) in organizations, and several insights have been discovered through this work. One is that firms search close to their current knowledge-bases (Nelson and Winter, 1982), and that searching further than that is rare and risky (Katila, 2002). Another is that successful search often combines knowledge that is know...

It’s never too early to get it Right

For centuries, scientists and physicians have been captivated by the consistent left-right (LR) asymmetry of the heart, viscera, and brain. A recent study implicated tubulin proteins in establishing laterality in several experimental models, including asymmetric chemosensory receptor expression in C. elegans neurons, polarization of HL-60 human neutrophil-like cells in culture, and asymmetric o...

Ondine's curse--never too late.

a normal life span. It has recently been shown that CCHS confers risk for adverse neurocognitive outcome [3]. Visuoperceptual reasoning and clerical/ visuographic speed appear particularly vulnerable. In this issue of IMAJ, Cohen-Cymberknoh and colleagues [4] present an interesting and unusual case of a 12 year old girl with late-onset CCHS that was suspected and diagnosed only after she failed...